A POSTDOCTORAL POSITION is available in our lab.
"The function of long non-coding RNAs transcribed from Prader-Willi syndrome locus"
Prader-Willi syndrome, transcription, ncRNA, direct RNA sequencing, induced pluripotent stem cells (iPSC)
The goal of the project is to understand the roles of non-coding RNAs (ncRNAs), the absence of which leads to neurodevelopmental disorder Prader-Willi syndrome (PWS). In particular, to investigate how individual PWS-related ncRNAs: sno-lncRNAs and SPA lncRNAs, regulate the transcriptome and thus, gene expression in human induced pluripotent stem cells (iPSC). Our approach will allow for precise dissection of functions for different RNAs missing in PWS and to understand their possible impact on differentiating cells.
The project will be performed in collaboration with Dr Paloma Garcia, Institute for Cancer and Genomics, University of Birmingham.
We are looking for a highly motivated, driven and enthusiastic person interested in RNA biology. Applicants should have a strong background in molecular biology, mammalian systems and "omics" approaches.
This full-time fixed-term post is funded by the Foundation for Prader-Willi Research for up to 12 months in the first instance. Full time starting salary (grade 7) is in the range of £30,942 to £40,322 a year.
Contact Dr Pawel Grzechnik about the post!!!!